Introduction Executive Summary Familial Lipoprotein Lipase Deficiency: Overview • Causes • Mechanism of Action • Signs and Symptoms • Diagnosis • Disease Management Pipeline Therapeutics • Comparative Analysis Therapeutic Assessment • Assessment by Product Type • Assessment by Stage and Product Type • Assessment by Route of Administration • Assessment by Stage and Route of Administration • Assessment by Molecule Type • Assessment by Stage and Molecule Type Familial Lipoprotein Lipase Deficiency – DelveInsight’s Analytical Perspective Late Stage Products (Phase III) • Comparative Analysis IONIS-APOCIII-LRx: Ionis Pharmaceuticals • Product Description • Research and Development • Product Development Activities Drug profiles in the detailed report….. Mid Stage Products (Phase II) • Comparative Analysis ARO-APOC3: Arrowhead Pharmaceuticals • Product Description • Research and Development • Product Development Activities Drug profiles in the detailed report….. Early Stage Products (Phase I/II) • Comparative Analysis Drug name: Company name • Product Description • Research and Development • Product Development Activities Drug profiles in the detailed report….. Preclinical/Discovery Stage Products • Comparative Analysis Lipisense: Lipigon Pharmaceuticals • Product Description • Research and Development • Product Development Activities Drug profiles in the detailed report….. Inactive Products • Comparative Analysis Familial Lipoprotein Lipase Deficiency Key Companies Familial Lipoprotein Lipase Deficiency Key Products Familial Lipoprotein Lipase Deficiency- Unmet Needs Familial Lipoprotein Lipase Deficiency- Market Drivers and Barriers Familial Lipoprotein Lipase Deficiency- Future Perspectives and Conclusion Familial Lipoprotein Lipase Deficiency Analyst Views Appendix

Table 1 Total Products for Familial Lipoprotein Lipase Deficiency Table 2 Late Stage Products Table 3 Mid Stage Products Table 4 Early Stage Products Table 5 Pre-clinical & Discovery Stage Products Table 6 Assessment by Product Type Table 7 Assessment by Stage and Product Type Table 8 Assessment by Route of Administration Table 9 Assessment by Stage and Route of Administration Table 10 Assessment by Molecule Type Table 11 Assessment by Stage and Molecule Type Table 12 Inactive Products

• Amryt Pharma • Arrowhead Pharmaceuticals • Ionis Pharmaceuticals • iMetabolic Biopharma • Precision Biosciences • Pfizer • Lipigon Pharmaceuticals