Introduction Executive Summary Narcolepsy: Overview • Causes • Mechanism of Action • Signs and Symptoms • Diagnosis • Disease Management Pipeline Therapeutics • Comparative Analysis Therapeutic Assessment • Assessment by Product Type • Assessment by Stage and Product Type • Assessment by Route of Administration • Assessment by Stage and Route of Administration • Assessment by Molecule Type • Assessment by Stage and Molecule Type Late Stage Products (Preregistration) • Comparative Analysis FT218: Avadel Pharmaceuticals • Product Description • Research and Development • Product Development Activities Drug profiles in the detailed report….. Mid Stage Products (Phase II) • Comparative Analysis TAK-994: Takeda • Product Description • Research and Development • Product Development Activities Drug profiles in the detailed report….. Early stage products (Phase I) • Comparative Analysis ADAIR: Vallon Pharmaceuticals • Product Description • Research and Development • Product Development Activities Drug profiles in the detailed report….. Inactive Products • Comparative Analysis Narcolepsy Key Companies Narcolepsy Key Products Narcolepsy- Unmet Needs Narcolepsy- Market Drivers and Barriers Narcolepsy- Future Perspectives and Conclusion Narcolepsy Analyst Views Narcolepsy Key Companies Appendix

Table 1 Total Products for Narcolepsy Table 2 Late Stage Products Table 3 Mid Stage Products Table 4 Early Stage Products Table 5 Pre-clinical & Discovery Stage Products Table 6 Assessment by Product Type Table 7 Assessment by Stage and Product Type Table 8 Assessment by Route of Administration Table 9 Assessment by Stage and Route of Administration Table 10 Assessment by Molecule Type Table 11 Assessment by Stage and Molecule Type Table 12 Inactive Products

• Axsome Therapeutics, Inc. • Avadel Pharmaceuticals • Suven Life Sciences • Takeda • NLS Pharmaceutics • Vallon Pharmaceuticals • Alkermes • Centessa Pharmaceuticals • Ono Pharma • Harmony Biosciences • Reset Therapeutics • XWPharma • Jazz Pharmaceuticals plc • Theranexus