Bone Grafts and Substitutes Market by Type (Bone Graft Substitutes, Allograft, Cell-based Matrices), Material Type (Collagen, Human Cell Source, Animal Source, Hydroxyapatite, Tricalcium Phosphate, Others), Application (Spinal Fusion, Trauma, Dental

"Market Definition:
The global bone grafts and substitutes market was valued at USD 2.96 billion in 2019 and is estimated to reach USD 4.85 billion by 2030, expanding at a CAGR of 4.5% during the forecast period from 2020 to 2030.
Bone grafting is a surgical procedure used to operate extremely complicated bone fractures. Bone grafts are implantable materials used during medical procedure to promote bone healing, bone formation, and osseous reconstruction. Depending on the grafting procedure, the bone grafts can be autologous, allograft, or synthetic with mechanical properties replicating the bone. These grafts are reabsorbed and replaced with the healing of natural bone. Their efficacy depend on three basic principles such as osteoconduction, osteoinduction, and osteogenesis. Bone grafts are employed in a wide range of applications such as spinal fusion, trauma, dental bone grafting, craniomaxillofacial, joint reconstruction, and other bone grafting procedures.
According to World Population Ageing data provided by the United Nations, the global population aged 60 years or above was around 962 million in 2017, and is expected to reach 2.1 billion by 2050. Also, according to the report published by Center for Disease Control and Prevention, in 2017, 60% of the elderly population was affected by spinal deformities.
Market Dynamics and Trends:
Growing population affected by various ailments increases the demand for bone grafts and substitutes. Additionally, rising rate of spinal deformities, growing number of road accidents, sports injuries, surging incidences of joint disorders, hip fractures, osteoporosis and arthritis, especially in women, are fueling market growth. Also, growing demand for dental bone grafts, high adoption of minimally invasive surgeries, and benefits offered by health-care insurance agencies are contributing to the market growth.
However, high cost of bone grafting surgeries and complications associated with grafting procedures are hampering the bone grafts and substitutes market. On the other hand, factors such as increase in per-capita disposable income, advancements in healthcare infrastructures, growing number of orthopedic specialty hospitals, and increasing government initiatives offering low-cost medical services are expected to create opportunities for the market players.
Market Segmentations and Scope of the Study:
The bone grafts and substitutes market is divided based on type, application, end user, and geography. On the basis of type, the market is segmented into bone graft substitutes, allograft, and cell-based matrices. In terms of application, the market is segregated into spinal fusion, trauma, dental bone grafting, craniomaxillofacial, and joint reconstruction. Based on geography, the global bone grafts and substitutes market is fragmented into North America, Europe, Asia-Pacific, and Rest of the World (RoW).
Geographical Analysis
North America is expected to dominate the global bone grafts and substitutes market during the forecast period, accounting major share of the market due to the presence of a well-established orthopedic specialty healthcare infrastructures, superior reimbursement facility, high adoption of advanced medical technologies, high investments in R&D activities, and presence of key players in this region.
The market in Asia-Pacific, especially in emerging economies, is estimated to expand at a high CAGR during the forecast period owing to rapidly increasing geriatric population, growing adoption of bone grafts, substitutes in grafting modalities, and presence of large patient pool in the region.

Competitive Landscape

Key players in the global the bone grafts and substitutes market are Johnson & Johnson, Arthrex, Inc., Baxter International Inc., Zimmer Biomet Holdings, Integra LifeSciences Holdings Corporation, Wright Medical Group N.V., Stryker Corporation, Musculoskeletal Transplant Foundation, NuVasive, Inc., and Medtronic Plc., Inc.
KEY MARKET SEGMENTS:
• Global Bone Grafts and Substitutes Market –

By Type

o Bone Graft Substitutes
o Allograft
o Cell-based Matrices
• Global Bone Grafts and Substitutes Market –

By Application

o Spinal Fusion
o Trauma
o Dental Bone Grafting
o Craniomaxillofacial
o Joint Reconstruction
• Global Bone grafts and substitutes Market – By Geography
o North America
 U.S.
 Canada
 Mexico
o Europe
 UK
 Germany
 France
 Italy
 Spain
 Rest of Europe
o Asia-Pacific
 China
 India
 Japan
 Australia
 South Korea
 Rest of Asia-Pacific
o RoW
 UAE
 Saudi Arabia
 South Africa
 Brazil
 Remaining Countries

KEY PLAYERS:
• Baxter International Inc.
• Integra LifeSciences Holdings Corporation
• Arthrex, Inc.
• Johnson & Johnson
• Wright Medical Group N.V.
• Medtronic Plc.
• Zimmer Biomet Holdings, Inc.
• Stryker Corporation
• Musculoskeletal Transplant Foundation
• NuVasive, Inc."